Vol. 2 No. 3 (2025): Volume 2, Issue 3

View Vol. 2 No. 3 (2025): Volume 2, Issue 3

The rapid growth of multi‑omics data poses challenges in workflow integration, interactive responsiveness, and reproducibility. HiOmics 2.0 introduces a hierarchical task‑scheduling architecture that decouples lightweight interactive operations from intensive computational pipelines, reducing plot‑generation time from >30 s to <5 s —an over 80% improvement. The platform further integrates single‑cell transcriptomics, proteomics, metabolomics, pathogen detection, and Mendelian randomization, enabling end‑to‑end analysis from raw data to biological insight. With 453 integrated tools and serving users worldwide, HiOmics 2.0 provides an efficient, reproducible, all‑in‑one cloud solution for modern life‑science research. Image credit: Cover article.

Published: 2025-12-31

Articles

  • Revealing Causal Genes in Nasopharyngeal Carcinoma: An Integrated Approach of Mendelian Randomization and Single-Cell Sequencing

    Yuxiao He, Bin Han, Xuanyu Pan, Jianping Zhou, Tingwei Lv, Xingrao Li, Yongjian Zhou, Yani Yang, Tingting Liu, Yanling Hu (Author)

  • HiOmics 2.0: An All-in-One Intelligent Cloud Platform for Multi-Omics Analysis in Biomedical Research

    Zhining Zhang, Yuanyuan Tang, Yunlin He, Yong Xu, Zhiwei Lu, Kangming He, Hong Qiu, Yongjian Huang, Juan Huang, Honghong Pu, Yanling Hu (Author)

  • Dynamic Profiling of the Tumor Microenvironment in Lung Squamous Cell Carcinoma by Multidimensional Transcriptomics

    Dandan Sun, Zixuan Liu, Jiaqi Gu, Quanlei Wang, Anxin Gu (Author)

  • Advancing STEC Bioinformatics Training for the New Era

    Ming Chen, Hao Liang, Yanling Hu, Dijun Chen, Hong Li, Zunnan Huang, Li Ye, Jian Ren, Haixia Long, Chengjian Jiang, Guangfu Pang, Bihui Huang, Zexian Liu, Sanqiang Gong, Sanqi An, Xiaomin Wang, Shunhan Yao, Jianlong Li, Tianpeng Wang, Xiaoying Zhou, Bo Liu, Jiemei Chu, Pei Wang, Lili Xu, Tianci Wang, Mengze Nie, Rongquan He, Gang Chen, Dan-Dan Xiong, Guoying Li, Dan Wang, Jiandi Li, Kai Huang (Author)

Reviews

  • Artificial Intelligence for Single-Cell Biology: From Representation Learning to Predictive Modeling

    Wenxing Li, YUXIANG LUO (Author)

  • Crosstalk Between Gingival Mesenchymal Stem Cells and the Inflammatory Microenvironment

    Qilin Mai, Song Guo Zheng (Author)