Archives

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  Pioneering Insights in Cellular Innovation

  Vol. 1 No. 1 (2024)

  Welcome to the inaugural issue of iCell, a cutting-edge journal dedicated to exploring the dynamic world of cellular biology and biomedical advancements. In this issue, we bring together a collection of groundbreaking research that pushes the boundaries of our understanding of cellular mechanisms, artificial intelligence in biology, and therapeutic innovations. From novel insights into gene regulation to transformative technologies in precision medicine, iCell serves as a platform for thought leaders and innovators to share their pioneering discoveries. Join us as we embark on a journey to shape the future of biomedical science.Image credit: The current article.

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  Immunotherapy and Informatics

  Vol. 2 No. 1 (2025)

  The convergence of immunotherapy and informatics has revolutionized precision cancer care and immune-related disease management. Informatics tools, including machine learning algorithms, multi-omics data integration platforms, and predictive modeling, enable researchers to decode complex immune system dynamics—such as tumor microenvironment heterogeneity, immune cell trafficking, and patient-specific immune signatures.

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  Volume 2, Issue 2

  Vol. 2 No. 2 (2025)

  The direct transdifferentiation of fibroblasts into specific functional cells offers a highly promising new cell source for regenerative medicine. In this issue of iCell, Wang, Huang, and colleagues elucidate the pivotal role of JNK1 downregulation in the transdifferentiation process of fibroblasts into mammary epithelial cells. This study reveals how the TGFβR1-JNK1 signaling axis functions as a molecular switch for cell fate determination, with its regulation contributing to the understanding of cellular plasticity and the development of novel strategies for mammary gland regeneration. Image credit: Cover article.